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Researcher 2

Ohio State University Wexner Medical Center
United States, Ohio, Columbus
281 West Lane Avenue (Show on map)
Jan 08, 2025

A full time Researcher position is available in the laboratory ofDr. Chenran Wangin theDepartment of Radiation Oncology. The researcher is dedicated to studying autophagy functions in glia for breast cancer brain metastasis.The Wanglaboratory also focuses onthe functions and mechanisms of selective autophagy and lipid metabolisms in neural stem cells, microglia, and astrocytes.

The lab developed novel genetically engineered mouse models to study roles of autophagy genes in brain developmental and in progress of breast cancer brain metastasis.We use a variety of techniques including single cell RNA-seq, single nuclei RNA-seq, single cell lineage tracing, human iPSC derived cerebral organoids, chemogenetics, clarity technique, patch clamp, super-resolution images, metabolic/molecular/cellular approachestogain insights in autophagys functions in human developmental disorders and breast cancer brain metastasis.

Required Experience

  • Master's Degree or equivalent experience required; PhD preferred.

  • 4-5 years of relevant experience required.

  • 5-7 years of relevant experience preferred.

  • At least one year of experience in neuroscience research, cell and molecular biology, or cancer biology preferred.

Additional Qualifications Considered

  • Experience in neural stem cell, cancer biology, signal transduction, metabolism, autophagy, glia cells, organoids, and genetic mouse models.

  • Experience in scRNAseq and snRNAseq is ideal.

  • Good oral and written communication skills.

  • Ability to work and collaborate effectively with students, faculty and staff from a variety of culturally diverse backgrounds.

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