New

Research Associate II- Center for Human Brain Variation

Broad Institute
paid time off, paid holidays, 401(k), retirement plan
United States, Massachusetts, Cambridge
Nov 03, 2025
Description & Requirements The Broad Institute of MIT & Harvard is looking for an outstanding Research Associate II to join the experimentalist team in the Center for Human Brain Variation. The mission of the project is to address an unmet need in cell census research: to understand the cell-type-specific mechanisms and larger tissue-level biological principles that generate meaningful variation in brain biology among people. We are seeking a highly motivated, collaborative Research Associate to support this important effort in close collaboration with other project scientists. The Research Associate should be able to conduct bench experiments with minimal supervision and will have opportunities to present at lab meetings and contribute to writing experimental protocols. RESPONSIBILITIES * Contribute to experimental workflows for profiling the molecular contents and biological states of thousands of individual cells in brain tissue, contributing to all aspects including planning experiments; creating DNA-barcoding reagents; extracting nuclei from human brain tissue; preparing molecular libraries; and high-throughput sequencing * Optimize and execute molecular-biological reactions such as PCR, DNA extractions from human brain tissue, and next generation sequencing (NGS) library preparation * Maintain meticulous records and document all experiments in the lab notebook * Attend and contribute to team meetings * Contribute to generation and optimization of experimental protocols QUALIFICATIONS * Bachelor's degree in biology, neuroscience, chemistry or a related field with 2+ years of related experience, or Master's degree with at least 1 year of related experience * Experience generating single-cell RNAseq, ATACseq, and multiome data preferred but not required. * Ability to critically read and discuss scientific research publications. * Strong ability to work both independently and collaboratively. * Excellent written and verbal communication skills. * Ability to thrive in a fast-paced rapidly changing environment. * Must be comfortable and able to work onsite five days per week. The expected base salary range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law. At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits. The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations. Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.