Lipid Nanoparticle & mRNA Synthesis Intern

Sartorius is a leading technology provider to the life sciences and biopharma industries, actively shaping dynamic, innovative, and highgrowth markets. To drive the creation of new solutions, Sartorius has formed a global Corporate Research initiative that identifies emerging trends and rapidly translates them into nextgeneration technology solutions. As part of our team in Marlborough, we are seeking a highly motivated intern with a multidisciplinary background in biomedical and bioengineering.

*Onsite role based at our Marlborough, MA site*

What you will accomplish together with us:

• Establish, execute, and maintain protocols for the preparation and characterization of lipid nanoparticle (LNP) formulations encapsulating nucleic acid cargo using automated LNP synthesis platforms.
• Perform in vitro assays to assess transfection efficiency and delivery of nucleic acids using formulated LNPs in mammalian cell systems.
• Conductsystematic experiments of in vitro transcription (IVT) reaction on benchtop bioreactors; collect and analyze the data.
• Support process development activities for LNP screening, scale-up, and manufacturing-relevant workflows.
• Troubleshoot issues with experimental design and execution.
• Collect, analyze, and interpret experimental data; prepare technical summaries and present results in internal meetings and reviews.

What will convince us:

Education

• PhD graduate or student in biomedical, chemical, mechanical engineering, or related field with formal education and experience with lipid nanoparticles and/or nucleic acids.

Experience

• Hands-on laboratory work including mammalian cell culture and handling of RNA.
• Experience with LNP formulation characterization techniques and biological assays used to evaluate key LNP properties
• Ideal to have an experience with one or more of the following: dynamic light scattering (DLS), nanoparticle tracking analysis, RiboGreen assay, HPLC
• Familiarity with nanoparticle formulation, microfluidics instruments, laboratory automation, chromatography (AKTA), advanced cell models, in vivo animal models, and in vitro transcription is plus.
• Strong oral and written communication and presentation skills.
• Identification with our core values: Sustainability, Openness, Enjoyment

What We Offer

As a growing global life science company, with our stock listed on the German DAX and TecDAX , Sartorius offers a wide range of benefits:
Personal and Professional Development: Mentoring, leadership programs, internal seminar offerings
Making an Impact Right from the Start: Comprehensive onboarding, including a virtual online platform
Welcoming Culture: Mutual support, team spirit and international collaboration; communities on numerous topics such as "Coaching", "Agile Working" and a "Businesswomen's Network"
Intelligent Working Environment: Working in smart buildings with the latest technology and equipment.

Compensation is up to $30 an hour. No relocation and/or accommodations are offered.

Sartorius is an equal opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, national origin, age, protected veteran status, disability or based on status in any other protected group of class.

Please view equal employment opportunity posters provided by OFCCP here.

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Sartorius is part of the solution in the fight against cancer, dementia, and many other diseases. Our technologies help translate scientific discoveries into real-world medicine faster, so that new therapeutics can reach patients worldwide. We look for ambitious team players and creative minds, who want to contribute to this goal and advance their careers in a dynamic global environment. Join our global team and become part of the solution. We are looking forward to receiving your application.

We look forward to receiving your application.

www.sartorius.com/career

If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening. You can request reasonable accommodation by e-mail at accommodationrequest@sartorius.com

Sartorius is an equal opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, national origin, age, protected veteran status, or disability, or based on status in any other protected group of class.

If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening. You can request reasonable accommodation by e-mail at accommodationrequest@sartorius.com

About Sartorius

Sartorius is part of the solution in the fight against cancer, dementia, and many other diseases. Our technologies help translate scientific discoveries into real-world medicine faster, so that new therapeutics can reach patients worldwide.

We look for ambitious team players and creative minds, who want to contribute to this goal and advance their careers in a dynamic global environment.

Join our global team and become part of the solution. We are looking forward to receiving your application.
www.sartorius.com/careers