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Postdoctoral Research Scientist

Columbia University
United States, New York, New York
535 West 116th Street (Show on map)
Apr 21, 2026

The Yang Lab studies fundamental mechanisms of cell-cycle regulation in normal and cancer cells, with a focus on how dysregulated cell-cycle control contributes to tumor heterogeneity and therapeutic resistance. We are seeking a curious, rigorous, and highly motivated postdoctoral Scientist to join our team and lead an exciting, well-supported research project in cell-cycle and cancer biology.

Our approaches

We integrate in vitro, in vivo, and human specimen studies using:




  • Live single-cell imaging to track heterogeneous populations, cell-cycle progression, and cancer cell evolution at single-cell resolution
  • Single-cell and bulk RNA-seq to define tumor progression and cell-state programs in mouse and human tissues
  • Multiplex single-cell and tissue imaging to map diverse cell populations in cell lines and the tumor microenvironment



Prior experience in any of these areas is welcomed but not required.

What you'll do




  • Lead an independent project on cell-cycle regulation and tumor heterogeneity
  • Design and execute experiments, analyze data, and interpret results with rigor
  • Prepare manuscripts and contribute to grant-supported research aims
  • Present findings at internal and external meetings
  • Mentor trainees (students/technicians) as appropriate


Columbia University is an equal opportunity employer. We value diversity and welcome applications from individuals of all backgrounds.

Minimum Education Requirements:



  • PhD or MD/PhD (completed or near completion) in cell biology, cancer biology, molecular biology, bioengineering, computational biology, or a related field


Minimum Skills Required:



  • Strong experimental and/or computational skills; a quantitative mindset is a plus
  • Demonstrated productivity (e.g., publications, preprints) and clear scientific communication
  • Collaborative, proactive, and problem-solving approach to research

Columbia University is an Equal Opportunity Employer / Disability / Veteran

Pay Transparency Disclosure

The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

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