Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 85 |
Director, Global Compensation - Commercial
Cambridge, Massachusetts
Overview We are seeking a Director, Global Compensation, to serve as the lead compensation partner for Alnylam's Global Commercial organization. This individual will provide strategic compensation expertise across base pay, market competiti...
14h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview Alnylam Pharmaceuticals is seeking a highly technical and strategic Director of Artificial Intelligence to lead the expansion of AI capabilities across the Research organization. This role will establish and lead a focused team to ...
14h
| Job Type | Full Time |
Associate Director, Field Reimbursement - Northwest Region
Cambridge, Massachusetts
Overview: Reporting to the Field Reimbursement Director, Lead, the Associate Director, Field Reimbursement will optimize access to Alnylam products in his/her region by understanding and addressing reimbursement and patient access challenge...
14h
| Job Type | Full Time |
Associate Director, Nonclinical Writing AI Innovation
Cambridge, Massachusetts
Overview The Associate Director, Nonclinical Writing Innovation, will lead the strategy and adoption of AI-enabled capabilities across nonclinical workflows. This high-visibility role will translate organizational priorities into scalable d...
14h
| Job Type | Full Time |
Senior Associate Scientist, In Vivo Technical Support Team
Cambridge, Massachusetts
Overview The qualified candidate is responsible for organizing, conducting, and reporting non-GLP rodent toxicology, investigative, and pharmacokinetics/toxicokinetic (PK/TK) studies that support drug discovery and development. An understan...
14h
| Job Type | Full Time |
Cambridge, Massachusetts
Sr. Manager, Global Planning Job Description Summary: Key contributor to clinical supply and operations planning monthly team meeting (CS&OP). Contribute and advise on Partner Sales and Operation Demand Reviews. Work cross-functionally to d...
23h
| Job Type | Full Time |
Senior Director, Head of PV Science
Cambridge, Massachusetts
Overview Alnylam is the industry leader in the translation of RNA interference (RNAi) into a new class of innovative medicines with the potential to address the unmet needs of patients with debilitating diseases. Founded in 2002, Alnylam wa...
1d
| Job Type | Full Time |
Associate Director, Biostatistics
Cambridge, Massachusetts
The Associate Director, Biostatistics is responsible for statistical activities in support of clinical trials, including contributing to trial designs, authoring statistical sections of protocols, preparing statistical analysis plans, and r...
1d
| Job Type | Full Time |
Senior Associate Scientist, Investigative Sciences
Cambridge, Massachusetts
Overview The Investigative Sciences team within the Early Development Department at Alnylam is seeking a highly motivated and experienced Senior Associate Scientist to join an interdisciplinary team dedicated to expanding the reach of RNAi ...
1d
| Job Type | Full Time |
Senior Manager, Commercial Training and Development
Cambridge, Massachusetts
Overview The Senior Manager, US Commercial Training & Development - TTR Franchise reports to the Associate Director. This role involves developing and implementing capability building strategies, plans and processes that drive measurable fi...
1d
| Job Type | Full Time |